Complete Aligner Cleaning Guide: Do’s, Don’ts, and Best Practices
Clear aligners like Invisalign® are designed to be nearly invisible, but only if they’re properly cared for. Without the right aligner cleaning routine, trays can quickly become cloudy, smelly, and even harbor harmful bacteria. This guide covers everything you need to know: the do’s, don’ts, and best practices to keep your aligners clear and hygienic throughout treatment.
Why Proper Aligner Cleaning Matters
Your aligners sit directly against your teeth for 20+ hours a day. If not cleaned correctly, they can:
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Trap plaque and bacteria against your teeth
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Cause bad breath and odors
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Stain or discolor, making them noticeable
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Shorten their lifespan
By using safe products like retainer cleaner tablets or professional Invisalign cleaners, you can keep trays crystal clear without damaging them.
Shocking Risks of a Dirty Invisalign: Could Your Neglect Lead to Serious Health Issues?
Skipping regular invisalign cleaning can turn it into a breeding ground for harmful bacteria, leading to infections, Bad breath, and even damage to your teeth and gums. This isn’t just about hygiene—it’s about protecting your health. Don’t wait until it’s too late.

Want to see exactly how to clean your retainer or aligner the right way?
We’ve added a quick video tutorial below to show you step-by-step how to remove bacteria, stains, and odor — without damaging your trays. Whether you're using Invisalign or a clear retainer, this visual guide makes it easy to follow along and keep your trays looking like new.
Do’s of Aligner Cleaning
1. Rinse Every Time You Remove Them
Always rinse aligners under lukewarm water before reinserting. This removes food particles and reduces bacteria growth.
2. Use a Gentle Brushing Technique
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Use a soft-bristle toothbrush
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Skip toothpaste (too abrasive)
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Gently brush aligners inside and out
3. Deep Clean with the Right Products
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Retainer cleaner tablet – Affordable, safe, and effective
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Invisalign cleaning crystals – Specially designed for Invisalign users
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Mild baking soda soak – A natural backup option
4. Store in a Case
Never wrap aligners in tissue (easy to lose or throw away). Always use the case provided by your orthodontist.
Don’ts of Aligner Cleaning
1. Don’t Use Hot Water
Heat can warp the plastic, ruining the fit.
2. Don’t Use Toothpaste or Harsh Chemicals
Avoid products like:
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Toothpaste (scratches plastic)
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Mouthwash (can stain trays)
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Bleach or household cleaners (toxic and damaging)
3. Don’t Eat or Drink with Aligners In
Only water is safe. Food and drinks can stain aligners and allow bacteria to thrive.
Best Practices for Aligner Cleaning
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Clean aligners twice a day just like brushing your teeth.
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Soak aligners 3–4 times per week in either a retainer cleaner tablet solution or Invisalign crystal cleaners.
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Keep aligners clear by rinsing them before reinserting after every meal.
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Rotate cleaning methods — a daily rinse, brushing, and weekly deep clean gives the best results.
Comparing Aligner Cleaning Methods
| Cleaning Method | Pros | Cons | Best Use Case |
|---|---|---|---|
| Brushing with water | Quick, easy, no cost | Doesn’t fully remove bacteria/odor | Daily use |
| Retainer cleaner tablet | Safe, removes plaque/odor, convenient | Needs soak time | Weekly deep clean |
| Invisalign cleaning crystals | Dentist-approved, powerful | More expensive | Invisalign-specific cleaning |
| DIY baking soda soak | Cheap, natural, chemical-free | Less effective, not daily use | Emergency/backup solution |
Recommended Products
Weiss Naturals Retainer Cleaner Tablets
A persulfate-free option, safe for daily or weekly use. Removes odor, buildup, and stains without harsh chemicals.
👉 Check Weiss Naturals reviews on Amazon.
Customer reviews:
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“I’ve tried several brands, but Weiss Naturals is the only one that keeps my aligners truly clear. No irritation at all!”
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“Affordable, easy to use, and effective. My aligners look brand new after every soak.”

Invisalign Cleaning Crystals
Trusted and specifically designed for Invisalign trays. Breaks down bacteria and plaque while keeping trays clear.
Gentle Baking Soda Solution
An occasional DIY method if you don’t have cleaner tablets on hand.
FAQ: Complete Aligner Cleaning
How often should I clean my aligners?
Rinse every time you remove them and give them a deeper clean 3–4 times per week with a retainer cleaner tablet or Invisalign cleaner.
Can I use toothpaste on aligners?
No. Toothpaste is abrasive and can scratch the aligner surface, causing them to discolor and trap bacteria.
Are Invisalign cleaning crystals safe?
Yes. Invisalign cleaning crystals are specifically formulated for Invisalign aligners and safe for regular use.
Which is better: retainer cleaner tablets or Invisalign crystals?
Both are effective:
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Retainer cleaner tablet – Affordable, general use.
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Invisalign crystal cleaners – Designed for Invisalign, slightly more expensive.
Final Thoughts
Maintaining your aligners doesn’t need to be complicated. By following these do’s, don’ts, and best practices, you’ll keep your trays clear, odor-free, and safe to wear. The best results come from combining daily rinsing with a trusted retainer cleaner tablet or Invisalign crystal cleaner.
Disclaimer:
The content in this article is for informational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider before making any changes to your health regimen. The author and publisher do not take responsibility for any consequences resulting from the information provided in this article.

Meet Dr. Jessica Cohen
Dr. Jessica Cohen, DMD, MS is a Board-Certified Orthodontist serving the Deerfield area with over a decade of experience. As a devoted mom to three girls — Scarlett, Shiloh, and Schuyler — she knows the value of creating a warm, welcoming environment for patients of all ages. Passionate about crafting confident, healthy smiles, Dr. Cohen blends science and artistry through her background in studying the esthetics of beauty pageant winners. She proudly recommends Weiss Naturals Persulfate-Free Retainer Cleaner tablets by B. WEISS to her patients — and even her own kids use it daily— for its gentle yet effective formula that keeps retainers fresh without harsh chemicals. It’s her trusted solution for safe, everyday care.
Related product

Meet Dr. Jessica Cohen
Dr. Jessica Cohen, DMD, MS is a Board-Certified Orthodontist serving the Deerfield area with over a decade of experience. As a devoted mom to three girls — Scarlett, Shiloh, and Schuyler — she knows the value of creating a warm, welcoming environment for patients of all ages. Passionate about crafting confident, healthy smiles, Dr. Cohen blends science and artistry through her background in studying the esthetics of beauty pageant winners. She proudly recommends Weiss Naturals Persulfate-Free Retainer Cleaner tablets by B. WEISS to her patients — and even her own kids use it daily— for its gentle yet effective formula that keeps retainers fresh without harsh chemicals. It’s her trusted solution for safe, everyday care.